Ebola Virus Pathogenesis: Implications for Vaccines and Therapies
GP is the only one of the seven Ebola virus gene products to exert this effect, and though GP from all four documented Ebola virus strains acts similarly, the highly pathogenic Zaire strain has the most potent activity in this cell culture assay (33). Nabel* Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland Ebola virus is an aggressive pathogen that causes a highly lethal hemorrhagic fever syndrome in humans and nonhuman primates
Xenobiotic metabolism a series of enzymatic reactions that convert a foreign chemical compound into an inert substance that can be safely excreted from the body. HDL-cholesterol is considered "good cholesterol," because higher blood levels of HDL-cholesterol are associated with lower risk of cardiovascular disease
Animal Cell Mitosis
Some mitotic spindle fibers elongate from the centrosomes and attach to kinetochores, protein bundles at the centromere region on the chromosomes where sister chromatids are joined
Interactive Eukaryotic Cell Model
Smooth ER plays different functions depending on the specific cell type including lipid and steroid hormone synthesis, breakdown of lipid-soluble toxins in liver cells, and control of calcium release in muscle cell contraction. Smooth Endoplasmic Reticulum: Throughout the eukaryotic cell, especially those responsible for the production of hormones and other secretory products, is a vast network of membrane-bound vesicles and tubules called the endoplasmic reticulum, or ER for short
The animal kingdom is unique among eukaryotic organisms because most animal tissues are bound together in an extracellular matrix by a triple helix of protein known as collagen. The process of cell fractionation enables the scientist to prepare specific components, the mitochondria for example, in large quantities for investigations of their composition and functions
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